Pharmaceutical parenteral closures demand the best
The DIRECT IMPACT CLEANING with high pressure
wash and rinse
sprays insures removal of particles, manufacturing soils,
and pyrogens. The result is total cleaning of all
surfaces including recessed
blind holes which retain water, particulates
and silicone (from
pre-siliconization by stopper manufacturer) due to
capillary action. The entire outer drum surfaces are cleaned so that
silicone and particulates go to drain.
Contamination of stoppers BEFORE
Contamination of stoppers a
The DIRECT IMPACT CLEANING guarantees
required shearing action is applied to dislodge the pyrogens
off the stoppers.
It also insures that the stoppers are individually
flushed clean and the
particles are drained. This process is repeatable
and gives fully validatable
A detailed technical animation of the
HUBER System process
is available upon request.
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